Description

Imdermalab® M-Guard is a natural active derived from mango leaves harvested in Yujing (Tainan, Taiwan), a region renowned for its rich mangiferin content. Developed using Cyclodextrin-based Supramolecular Assembly Technology, M-Guard delivers enhanced stability, penetration, and bioavailability. It provides potent antibacterial, sebum-regulating, antioxidant, and collagen-support benefits to rebalance and purify the skin for a clear, matte, and refreshed appearance

Benefit

• Antibacterial action against S. aureus and P. acnes.
• Sebum regulation via inhibition of fatty-acid desaturation for balanced oil control
• Collagen support by stimulating fibroblast proliferation (HS68 cells)
• Antioxidant protection comparable to Vitamin C at the same dosage
• Instant oil-control and soft-matte finish demonstrated in in-vivo tests

Mechanism of action

• Mangiferin in M-Guard disrupts bacterial membranes and inhibits metabolic and protein-synthesis enzymes, providing multi-level antibacterial defense. It suppresses fatty-acid desaturation to reduce sebum synthesis and excess oil production, while its polyphenolic structure neutralizes ROS and lipid peroxidation, supporting collagen synthesis and skin firmness

Tests

Application

• Ideal for oil-control and microbiome-balancing skincare such as gels, serums, lotions, and masks.